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Stephen Fung & Keung To in thinking & confident pose

平均每2位男士便有1位
有機會感染HPV2b
只有少數男性感染HPV後
可產生足夠抗體3若持續感染
可能會演化成頭頸癌4*

本港約2/3頭頸癌新症案例為男性4c,5d
頭頸癌包括:口咽癌,喉癌,口腔癌,舌癌等6

*大多數HPV感染可自行清除,但持續感染且無法自行清除可導致某些相關疾病7

Graphic icon indicating 90% & 70% of HPV caused disease

男性感染HPV的影響

90%

以上的肛門癌及90%以上椰菜花都是由HPV而起7,8

70%

的頭頸癌都和HPV有關9

HPV可引發頭頸癌?

人類乳頭瘤病毒(Human Papilloma Virus, HPV)主要透過性行為接觸到皮膚、黏膜或體液感染10,除了性器官,男女也可能因性相關接觸導致HPV感染,引發頭頸癌9,11

頭頸癌泛指影響上呼吸消化道不同解剖部位粘膜內層的惡性腫瘤,包括鼻咽、鼻竇、口腔、口咽、下咽和喉部6。在過去幾十年中,人類乳頭瘤病毒(HPV)已成為這些癌症的新危險因素,尤其是口咽鱗狀細胞癌 6。普遍而言,男性患上頭頸癌的機率比女性高。根據香港癌症治療統計中心的數據,在2021年,患上頭頸癌(唇,舌,涎腺,口腔,扁桃體、口咽,下咽,其他口腔未列明部位,鼻腔、中耳及副鼻竇,喉),有3分之2的患者為男性。4c,5d

即’Click’以下各種頭頸癌了解更多資訊

感染HPV有幾大件事?

Graphic icon of a sperm being crossed out

有機會導致不育

不論男女,肛門癌放射治療可能引致不育13

Graphic icon with germs on an infinite loop

HPV感染容易復發難斷尾

以椰菜花為例,患者有機會不斷復發,難以斷尾14

你知道嗎?

本港男性椰菜花患者人數為女性的3.3倍15e
HPV感染患者更有高達75%機會傳染給性伴侶14

Graphic icon with male & female symbol, where germs and a feutus inside the symbols

傳染給伴侶的風險

男性將致癌HPV傳染給女性的風險比女傳男高約5倍16f,致癌HPV有機會誘發女性患子宮頸癌7

有機會影響下一代?

HPV有機會經母嬰傳播。
日本更有案例嬰兒疑因吸入母親體內子宮頸癌細胞而罹患肺癌17,18

懂得保護女性,更Man!

世界衛生組織更指出,
子宮頸癌為目前唯一有望根除的癌症19g
然而現時全球每年約有50多萬的新病例,
更有數十萬女性死亡19
在香港,平均每2-3日便有一位女士
因爲子宮頸癌被逼離開最愛的家人20h

A confident Keung To on top of green teared paper background

a 一項美國研究指出14-59歲中,男性感染高致癌風險HPV的盛行率為25.7%,而女性為20.7%1
b 在巴西,墨西哥及美國18-70歲數男士中, 男性生殖器官HPV感染的盛行率高達65.1%
c 約70%口咽癌與HPV感染有關4
d 根據2021年醫管局癌症資料庫顯示,男性頭頸癌(唇,舌,涎腺,口腔,扁桃體、口咽,下咽,其他口腔未列明部位,鼻腔、中耳及副鼻竇,喉)新症個案佔整體約2/35
e 根據2021年衛生署資料顯示15
f 基於中國農村人口隊列研究所得16
g 按照WHO定義,子宮頸癌作為一個公共衛生問題被消滅,是指發病率不超過4宗每十萬女性人年19
h 根據2021年資料顯示子宮頸癌死亡個案為178宗20

References: 1. Lewis, R.M., et al. J Infect Dis. 2018; 217 (6): 869–77. 2. Giuliano, A.R., et al. Cancer Epidemiol Biomarkers Prev 2008; 17(8): 2036–43. 3. Giuliano, A.R., et al. Papillomavirus Res. 2015;1:109‒15. 4. CDC. Head and Neck Cancers. Available at: https://www.cdc.gov/cancer/headneck/index.htm. Accessed on: 19 Apr 2024. 5. Hong Kong Cancer Registry, Hong Kong Authority. Available at: https://www3.ha.org.hk/cancereg/allagesresult.asp. Accessed on: 19 Apr 2024. 6. Sabatini ME & Chiocca S. British Journal of Cancer. 2020; 122: 306–14. 7. National Cancer Institute. HPV and Cancer. Available at: https://www.cancer.gov/about-cancer/causes-prevention/risk/infectious-agents/hpv-fact-sheet. Accessed on: 19 Apr 2024. 8. Centre for Health Protection. Sept 2016. Available at: https://bit.ly/3Qqk7Vk. Accessed on: 19 Apr 2024.  9. Center for Disease Control and Prevention. HPV and Oropharyngeal Cancer. Available at: https://www.cdc.gov/cancer/hpv/basic_info/hpv_oropharyngeal.htm#:~:text=HPV%20can%20infect%20the%20mouth,cancers%20in%20the%20United%20States. Accessed on: 19 Apr 2024. 10. Health Promotion Administration, Ministry of Health and Welfare. QA. Available at: https://www.hpa.gov.tw/Pages/List.aspx?nodeid=1799. Accessed on: 19 Apr 2024.11. National Cancer Institute. Head and Neck Cancer. Available at: https://www.cancer.gov/types/head-and-neck/head-neck-fact-sheet#what-are-head-and-neck-cancer-symptoms. Accessed on: 19 Apr 2024. 12. American Society of Clinical Oncology Cancer Net. Head and Neck Cancer: Types of Treatment. Available at: https://www.cancer.net/cancer-types/head-and-neck-cancer/types-treatment. Accessed on: 19 Apr 2024. 13. American Cancer Society, Radiation Therapy for Anal Cancer. Available at: https://www.cancer.org/cancer/anal-cancer/treating/radiation-therapy.html. Accessed on: 19 Apr 2024. 14. Yanofsky, V.R., et al. The Journal of Clinical and Aesthetic Dermatology. 2012;5(6): 25–36. 15. Centre for Health Protection. Men’s Health Line – Genital Wart. Available at: https://www.chp.gov.hk/en/static/80039.html. Accessed on: 19 Apr 2024.  16. Liu, M., et al. Sci Rep. 2015;5:10986.  17. Sabeena, S., et al. J Obstet Gynaecol Res. 2017;43(3):429–35. 18. Arakawa, A., et al. N Engl J Med. 2021;384: 42–50. 19. WHO. 2020. Global strategy to accelerate the elimination of cervical cancer as a public health problem. 20. Hong Kong Cancer Registry, Hospital Authority. Cervical Cancer in 2021. Oct 2023. Available at: https://www3.ha.org.hk/cancereg/pdf/factsheet/2021/cx_2021.pdf Accessed on: 19 Apr 2024. 

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