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感染某些高危型HPV,
如HPV 16和18,可導致
約90%子宮頸癌及約90%肛門癌

低危型HPV
主要引致生殖器官濕疣(俗稱椰菜花)
超過90%椰菜花
由HPV 6及11引起。


大部分的HPV感染通常不會有病徵,
潛伏期可高達10年,更會人傳人4

若無法自行清除,感染HPV到現在
仍然沒有針對性治療方法,
持續感染手尾長,更有機會導致癌症4



大部分
子宮頸癌1

70%
外陰癌1*

75%
陰道癌1*

>90%
  肛門癌1*

90%
生殖器官濕疣3


治療方案只供參考,詳情請向醫生查詢


根據醫管局數據顯示, 在過去十年, 2 5 – 2 9 歲的子宮頸癌平均發病人數是 20-24歲的7倍,45-49歲女性更為確診 子宮頸癌數目的高峰6b
當子宮頸內細胞受到HPV的持續侵襲, 就可能導致細胞變異,引發子宮頸上皮內瘤 (CIN)。若CIN第3級得不到適當的治療,10年內演變成癌的機會約40%7

本港平均每2-3日便有一位女士 因爲子宮頸癌離開最愛的家人8c

b 2010-2019年十年來20-24歲的子宮頸癌平均新症數目為<1,而25-29歲為76
c 根據2019年資料顯示 子宮頸癌死亡個案為162宗8

病徵:肛門癌早期病徵與痔瘡相似,如有分泌物於股溝流出或肛門出血等9。一般人難以區分,以至延誤就醫10
治療方案:肛門癌可以透過肛門局 部/全切除手術、放射治療以及化學 藥物治療去治療11 – 13若進行肛門切除手術或需造外置造口,或會影響日常生活11

病徵: 椰菜花可以潛伏2星期至8個 月14椰菜花病徵為一個或多個結塊生長於生殖器官、生殖器官痕癢、排尿不尋常等14-15
治療方案:椰菜花治療方法包括冷凍治療法、手術切除、燒灼治療等14。但椰菜花難以斷尾,約4成患者至少復發1次16

本港平均每2-3日便有一位女士 因爲子宮頸癌離開最愛的家人8c

其他疾病亦存風險:外陰癌及陰道癌1

本港平均每2-3日便有一位女士 因爲子宮頸癌離開最愛的家人8c

a 根據2019年衛生署數據顯示14

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References:
1. National Cancer Institute. HPV and Cancer. Available at: https://www.cancer.gov/about-cancer/causes-prevention/risk/infectious-agents/hpv-fact-sheet . Accessed on 8 Apr 2022.
2. Ryser, M.D., et al. (2015). PLoS Comput Biol 11(3): e1004113.
3. Centre for Health Protection. Sept 2016.
4. CDC. Genital HPV Infection – CDC Fact Sheet, CDC. Available at: https://www.cdc.gov/std/hpv/HPV-FS-July-2017.pdf. Accessed on: 8 Apr 2022.
5. Data on File, MSD.
6. Hong Kong Cancer Registry, Hospital Authority. Hong Kong Cancer Statistics. Available at: https://www3.ha.org.hk/cancereg/allages.asp. Accessed on: 8 Apr 2022.
7. Hospital Authority. Cervical Cancer. Available at: https://www21.ha.org.hk/smartpatient/SPW/zh-HK/Disease-Inf ormation/Disease/?guid=90118916-92f8-4f99-b864-3c3f36a48b cca. Accessed on: 8 Apr 2022.
8. Hong Kong Cancer Registry, Hospital Authority. Cervical Cancer in 2019. Oct 2021. Available at: https://www3.ha.org.hk/cancereg/pdf/factsheet/2019/cx_2019 .pdf. Accessed on: 8 Apr 2022.
9. American Cancer Society. Signs and Symptoms of Anal Cancer. Available at: https://www.cancer.org/cancer/anal-cancer/detection-diagnos is-staging/signs-and-symptoms.html. Accessed on: 8 Apr 2022.
10. America Cancer Society. Can Anal Cancer Be Found Early? Available at: https://www.cancer.org/cancer/anal-cancer/detection-diagnos is-staging/detection.html. Accessed on: 8 Apr 2022.
11. American Cancer Society, Surgery for Anal Cancer. Available at: https://www.cancer.org/cancer/anal-cancer/treating/surgery.html. Accessed on: 8 Apr 2022.
12. American Cancer Society, Radiation Therapy for Anal Cancer. Available at: https://www.cancer.org/cancer/anal-cancer/treating/radiation-therapy.html. Accessed on: 8 Apr 2022.
13. American Cancer Society, Chemotherapy for Anal Cancer, 2019, Available at: https://www.cancer.org/cancer/anal-cancer/treating/chemotherapy.html. Accessed on: 8 Apr 2022.
14. Centre for Health Protection. Men’s Health Line ‒ Genital Wart. Available at: https://www.chp.gov.hk/en/static/80039.html. Accessed on: 8 Apr 2022.
15. National Health Service. Genital warts. Available at: https://www.nhs.uk/conditions/genital-warts/. Accessed on: 8 Apr 2022.
16. Giuliano AR et al. J Infect Dis. 2019;219:703-710.

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